James Seeb

  • Research Professor, SAFS

Research areas

My research focuses on identifying genetic differences that distinguish one Pacific salmon population from another. My current work uses genetic markers to track the migration of adult salmon in the North Pacific Ocean and Bering Sea. Students and post-docs in the Seeb Lab create genetic maps to enable genomic study of Chinook, sockeye, pink, and chum salmon and steelhead trout. My wife, Lisa Seeb, and I run the program, which provides an important intersection between the Alaska Salmon Program and the field of ecological genomics to conduct both basic and applied research. We want to better understand the genetic mechanisms underlying how salmon respond to environmental change.

Selected publications

  • Limborg, M.T., W.A. Larson, L.W. Seeb, and J.E. Seeb. 2017. Screening of duplicated loci reveals hidden divergence patterns in a complex salmonid genome. Mol Ecol 26(17): 4509-4522. 10.1111/mec.14201

  • McKinney, G.J., R.K. Waples, L.W. Seeb, and J.E. Seeb. 2017. Paralogs are revealed by proportion of heterozygotes and deviations in read ratios in genotyping-by-sequencing data from natural populations. Molecular Ecology Resources 17(4): 656-669. 10.1111/1755-0998.12613

  • McKinney, G.J., W.A. Larson, L.W. Seeb, and J.E. Seeb. 2017. RADseq provides unprecedented insights into molecular ecology and evolutionary genetics: comment on Breaking RAD by Lowry et al. (2016). Mol Ecol Resour 17(3): 356-361. 10.1111/1755-0998.12649

  • McKinney, G.J., L.W. Seeb, W.A. Larson, D. Gomez-Uchida, M.T. Limborg, M.S. Brieuc, . . . J.E. Seeb. 2016. An integrated linkage map reveals candidate genes underlying adaptive variation in Chinook salmon (Oncorhynchus tshawytscha). Mol Ecol Resour 16(3): 769-783. 10.1111/1755-0998.12479

  • Waples, R.K., L.W. Seeb, and J.E. Seeb. 2016. Linkage mapping with paralogs exposes regions of residual tetrasomic inheritance in chum salmon (Oncorhynchus keta). Mol Ecol Resour 16(1): 17-28. 10.1111/1755-0998.12394

  • Larson, W.A., L.W. Seeb, M.V. Everett, R.K. Waples, W.D. Templin, and J.E. Seeb. 2014. Genotyping by sequencing resolves shallow population structure to inform conservation of Chinook salmon (Oncorhynchus tshawytscha). Evol Appl 7(3): 355-369. 10.1111/eva.12128

  • Seeb, J.E., G. Carvalho, L. Hauser, K. Naish, S. Roberts, and L.W. Seeb. 2011. Single-nucleotide polymorphism (SNP) discovery and applications of SNP genotyping in nonmodel organisms. Molecular Ecology Resources 11: 1-8. 10.1111/j.1755-0998.2010.02979.x